Isothermal approach to assemble spatial DNA nanotubes for drug delivery

Carbon Nanotubes: a Promising Approach for Drug Delivery

Carbon Nanotubes: a Promising Approach for Drug Delivery

carbon nanotubes: a promising approach for drug delivery

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Carbon Nanotubes: a Promising Approach for Drug Delivery

The bioavailability and intrinsic toxicity of many potential drugs affect their pharmacological profile and, in turn, their therapeutic efficacy and therefore, preventing them from late-stage pharmaceutical development. Hence, pharmaceutical industries are recently being forced to renew creatively their drug discovery programs and design more and better drug candidates for clinical development....

Doxorubicin Loaded DNA Aptamer Linked Myristilated Chitosan Nanogel for Targeted Drug Delivery to Prostate Cancer

Recently, specific attention has been paid to aptamers, short DNA or RNA, as a tool for cancer diagnosis and therapy. In the present study MCS nanogels were prepared by Myristate: chitosan at 1:9 ratio and were characterized by several techniques. A selected ssDNA aptamer(Apt) capable of detecting LNCaP cells was linked to Myristilated chitosan nanogels (Apt-MCS) by glutaraldehyde and loaded wi...